ROME (AP) — Pope Francis is responding well to the treatment for double pneumonia and has shown a "gradual, slight improvement" in recent days, the Vatican said Saturday. But his doctors have decided to keep his prognosis as guarded, meaning that he's not out of danger yet.

The 88-year-old pope, who has chronic lung disease and had part of one lung removed as a young man, has remained stable, with no fever and good oxygen levels in his blood for several days, doctors reported in a Vatican statement.

The doctors said that such stability “as a consequence testifies to a good response to therapy.” It was the first time the doctors had reported that Francis was responding positively to the treatment for the complex lung infection that was diagnosed after he was hospitalized on Feb. 14.

Francis worked and rested during the day on Saturday, as he entered his fourth week at Rome’s Gemelli hospital with his condition stabilized following a few bouts of acute respiratory crises last week.

“In order to record these initial improvements in the coming days as well, his doctors have prudently maintained the prognosis as guarded,” the statement said.

In his absence, the Vatican's day-to-day operations continued, with Cardinal Pietro Parolin celebrating Mass for an anti-abortion group in St. Peter's Basilica. At the start, Parolin delivered a message from the pope from the hospital on the need to protect life, from birth to natural death.

In the message, dated March 5 and addressed to the Movement for Life, which seeks to provide women with alternatives to abortion, Francis encouraged the faithful to promote anti-abortion activities not just for the unborn, but “for the elderly, no longer independent or the incurably ill.”

Later Saturday, another cardinal closely associated with Francis' papacy, Canadian Cardinal Michael Czerny, presides over the nightly recitation of prayers for Francis. Czerny then returns on Sunday to celebrate the Holy Year Mass for volunteers that Francis was supposed to have celebrated.

Francis has been using high flows of supplemental oxygen to help him breathe during the day and a noninvasive mechanical ventilation mask at night.

Francis was hospitalized Feb. 14 for what was then just a bad case of bronchitis. The infection progressed into a complex respiratory tract infection and double pneumonia that has sidelined Francis for the longest period of his 12-year papacy and raised questions about the future.

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Associated Press religion coverage receives support through the AP's collaboration with The Conversation US, with funding from Lilly Endowment Inc. The AP is solely responsible for this content.

Vatican Secretary of State, Cardinal Pietro Parolin, delegated by Pope Francis who's being treated for pneumonia at Rome's Agostino Gemelli Polyclinic, presides over a mass with the pilgrims of the "Movement for Life" in St. Peter's Basilica at The vatican, Saturday, March 8, 2025. (AP Photo/Gregorio Borgia)

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Locals and tourists walk outside the Sant'Angelo castle as the sun sets in Rome, Italy, Friday, March 7, 2025. (AP Photo/Francisco Seco)

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Volunteers carry wooden crosses near St. Peter's Square in Rome, Italy, Friday, March 7, 2025. (AP Photo/Francisco Seco)

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A woman prays as she joins with others for a prayer of the Rosary for Pope Francis in St. Peter's Square at The Vatican, Friday, March 7, 2025. (AP Photo/Francisco Seco)

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Catholic nuns walk outside the Vatican city, in Rome, Italy, Friday, March 7, 2025. (AP Photo/Francisco Seco)

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The Sant'Angelo castle is illuminated as the sun sets in Rome, Friday, March 7, 2025. (AP Photo/Francisco Seco)

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Locals and tourists walk along a main street near St. Peter's Basilica, background, as the sun sets in Rome, Italy, Friday, March 7, 2025. (AP Photo/Francisco Seco)

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Tourists sit near Sant'Angelo castle, background, as the sun sets in Rome, Italy, Friday, March 7, 2025. (AP Photo/Francisco Seco)

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A nun prays for Pope Francis in front of the Agostino Gemelli Polyclinic, in Rome, Friday, March 7, 2025, where the Pontiff is hospitalized since Friday, Feb. 14. (AP Photo/Andrew Medichini)

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Candles for Pope Francis are seen in front of the Agostino Gemelli Polyclinic, in Rome, Friday, March 7, 2025, where the Pontiff is hospitalized since Friday, Feb. 14. (AP Photo/Andrew Medichini)

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Candles for Pope Francis are seen in front of the Agostino Gemelli Polyclinic, in Rome, Friday, March 7, 2025, where the Pontiff is hospitalized since Friday, Feb. 14. (AP Photo/Andrew Medichini)

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Vatican Secretary of State, Cardinal Pietro Parolin, delegated by Pope Francis who's being treated for pneumonia at Rome's Agostino Gemelli Polyclinic, presides over a mass with the pilgrims of the "Movement for Life" in St. Peter's Basilica at The vatican, Saturday, March 8, 2025. (AP Photo/Gregorio Borgia)

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A child follows Vatican Secretary of State, Cardinal Pietro Parolin, left background, delegated by Pope Francis who's being treated for pneumonia at Rome's Agostino Gemelli Polyclinic, presiding over a mass with the pilgrims of the "Movement for Life" in St. Peter's Basilica at The Vatican, Saturday, March 8, 2025. (AP Photo/Gregorio Borgia)

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Vatican Secretary of State, Cardinal Pietro Parolin, center, delegated by Pope Francis who's being treated for pneumonia at Rome's Agostino Gemelli Polyclinic, presides over a mass with the pilgrims of the "Movement for Life" in St. Peter's Basilica at The vatican, Saturday, March 8, 2025. (AP Photo/Gregorio Borgia)

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Vatican Secretary of State, Cardinal Pietro Parolin, left, delegated by Pope Francis who's being treated for pneumonia at Rome's Agostino Gemelli Polyclinic, presides over a mass with the pilgrims of the "Movement for Life" in St. Peter's Basilica at The vatican, Saturday, March 8, 2025. (AP Photo/Gregorio Borgia)

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Flowers are left for Pope Francis in front of the Agostino Gemelli Polyclinic, in Rome, Saturday, March 8, 2025, where the Pontiff is hospitalized since Feb. 14. (AP Photo/Andrew Medichini)

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Candles and flowers are left for Pope Francis in front of the Agostino Gemelli Polyclinic, in Rome, Saturday, March 8, 2025, where the Pontiff is hospitalized since Feb. 14. (AP Photo/Andrew Medichini)

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Candles and flowers are left for Pope Francis in front of the Agostino Gemelli Polyclinic, in Rome, Saturday, March 8, 2025, where the Pontiff is hospitalized since Feb. 14. (AP Photo/Andrew Medichini)

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Nuns pray for Pope Francis in front of the Agostino Gemelli Polyclinic, in Rome, Saturday, March 8, 2025, where the Pontiff is hospitalized since Friday, Feb. 14. (AP Photo/Andrew Medichini)

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A nun takes photos in front of the Agostino Gemelli Polyclinic, in Rome, Saturday, March 8, 2025, where Pope Francis is hospitalized since Friday, Feb. 14. (AP Photo/Andrew Medichini)

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Nuns pray for Pope Francis in front of the Agostino Gemelli Polyclinic, in Rome, Saturday, March 8, 2025, where the Pontiff is hospitalized since Friday, Feb. 14. (AP Photo/Andrew Medichini)

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Nuns pray for Pope Francis in front of the Agostino Gemelli Polyclinic, in Rome, Saturday, March 8, 2025, where the Pontiff is hospitalized since Friday, Feb. 14. (AP Photo/Andrew Medichini)

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A view of the Agostino Gemelli Polyclinic, in Rome, Saturday, March 8, 2025, where Pope Francis is hospitalized since Friday, Feb. 14. (AP Photo/Andrew Medichini)

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A view of the Agostino Gemelli Polyclinic, in Rome, Saturday, March 8, 2025, where Pope Francis is hospitalized since Friday, Feb. 14. (AP Photo/Andrew Medichini)

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Nuns leave after they prayed for Pope Francis in front of the Agostino Gemelli Polyclinic, in Rome, Saturday, March 8, 2025, where the Pontiff is hospitalized since Friday, Feb. 14. (AP Photo/Andrew Medichini)

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Italian Carabinieri civil protection volunteers arrive to St. Peter's Basilica at The Vatican, Saturday, March 8, 2025. (AP Photo/Francisco Seco)

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Bishop Franco Agostinelli leads a rosary prayer for Pope Francis in front of the Agostino Gemelli Polyclinic, in Rome, Saturday, March 8, 2025, where the Pontiff is hospitalized since Friday, Feb. 14. (AP Photo/Andrew Medichini)

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